IVC with INVOcell.
INVOcell is the first ever FDA-cleared and CE-marked medical device for fertility treatment via intravaginal culture (IVC). During IVC, eggs, sperm and culture media are combined in the INVOcell device. The INVOcell is then placed in the upper vaginal cavity, allowing for fertilization and incubation to occur in a way similar to natural conception.
Keeping families connected
Unlike IVF, where eggs and sperm are combined in a lab, INVOcell holds the eggs and sperm inside the female body. This process provides the optimal environment for embryo development, and also keeps women closely connected to the experience.
Device features
Inner chamber
Holds the egg and sperm
Outer chamber
Protects the inner chamber
Retention device
Holds the outer chamber in place
How INVOcell works
During pre-treatment, patients undergo a personalized ovarian stimulation protocol. Patients then undergo the following IVC treatment steps.
Step 1
After the egg retrieval and sperm collection, they are placed in the INVOcell device for fertilization.*
*The clinician may recommend ICSI, a procedure which inseminates the egg prior to placement of the device.
Step 2
The device is then placed in the upper vaginal cavity to allow incubation to take place.
Step 3
Upon completion of the incubation period, the device is removed.
Step 4
An embryo is selected and transferred into the uterus. Any additional embryos can be frozen.
Your INVOcell questions — answered
The outer chamber is approximately 2.5 cm wide and 4.5cm tall. The retention device, which is similar to size to a diaphragm, is 70 mm in diameter.
Most women feel little to no discomfort when the INVOcell is in the body. There was a study presented at the 2021 American Society of Reproductive Medicine (ASRM) which showed that the INVOcell was well tolerated and did not cause irritation.
You should consult your physician, but you typically can go about your normal activities. You should avoid anything that is physically strenuous or anything that would change the temperature of your body like a hot bath or sauna. You should not swim, douche, have intercourse and/or insert objects or liquids into the vagina.
If the device becomes uncomfortable or moves call your physician.
Yes! In most cases one embryo is selected to be transferred to the uterus for further development. You and your physician will decide if more than one embryo should be transferred.